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Curr Opin Cell Biol. 2000 Aug;12(4):475-82.

Regulators and effectors of the ARF GTPases.

Author information

1
Laboratory of Cell Biology, NHLBI, NIH, Bethesda, 20892, USA. jdonalds@helix.nih.gov.

Abstract

The small G proteins of the ARF family are key regulators of membrane dynamics. Many functions of ARF proteins in cells are being revealed by studies of their regulators and effectors. Significant progress has been made over the past year, with the identification of a surprisingly large family of novel ARF GTPase-activating proteins. In addition, two new classes of effectors, the PIP kinases and a novel family of monomeric coat-like proteins have been discovered.

PMID:
10873831
DOI:
10.1016/s0955-0674(00)00119-8
[Indexed for MEDLINE]

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