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Curr Opin Cell Biol. 2000 Aug;12(4):509-16.

Divide and multiply: organelle partitioning in yeast.

Author information

1
Department of Biochemistry, University of Iowa, Iowa City, 52242, USA. natalie-catlett@uiowa.edu.

Abstract

The mechanisms ensuring accurate partitioning of yeast vacuoles and mitochondria are distinct, yet they share common elements. Both organelles move along actin filaments, and both organelles require fusion and fission to maintain normal morphology. Recent studies have revealed that while vacuolar inheritance requires a processive myosin motor, mitochondrial inheritance requires controlled actin polymerization. Distinct sets of proteins required for the fusion and fission of each organelle have also been identified.

PMID:
10873824
DOI:
10.1016/s0955-0674(00)00124-1
[Indexed for MEDLINE]

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