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Curr Opin Cell Biol. 2000 Aug;12(4):445-9.

Transport between ER and Golgi.

Author information

1
Department of Cell Biology, Institute of Biomembranes, Center for Biomedical Genetics, University Medical Center, Utrecht, 3584 CX, The Netherlands. J.Klumperman@lab.azu.nl.

Abstract

In the last eighteen months, it has become clear that some classes of proteins are actively recruited into endoplasmic reticulum export carriers, whereas others are exported as bulk-flow cargo. Subsequent transport to the Golgi is mediated by tubulovesicular membranes. The anterograde membrane flow is compensated for by a retrograde pathway, which, in addition to the recycling of membrane and proteins to the endoplasmic reticulum, may play a role in anterograde cargo concentration.

PMID:
10873822
DOI:
10.1016/s0955-0674(00)00115-0
[Indexed for MEDLINE]

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