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Chest. 2000 Jun;117(6):1656-60.

International comparison of median age at death from cystic fibrosis.

Author information

1
Division of Respiratory Medicine, City Hospital, University of Nottingham, UK. andrew.fogarty@nottingham.ac.uk

Abstract

STUDY OBJECTIVES:

To compare international trends in mortality from cystic fibrosis.

DESIGN:

Comparison of trends in median age at death using national mortality data.

SETTING:

Data from 10 countries in North America, Europe, and Australasia.

PARTICIPANTS:

All persons registered as having died of cystic fibrosis in specified years from 1980 to 1994.

INTERVENTIONS:

Comparison of relative odds of death at the international median age at death for the year of death between countries for two periods of time; from 1980 to 1987 (10 countries) and from 1980 to 1994 (7 countries).

MEASUREMENTS AND RESULTS:

The international median age at death increased from 8 years in 1974 to 21 years in 1994. Median age at death also increased within all countries, was consistently highest in the United States, and varied significantly by a factor of > twofold between countries. Women were significantly more likely to die at a younger age than the median age at death than men.

CONCLUSIONS:

Median age at death from cystic fibrosis is increasing, but our findings imply that clinically significant differences in survival with cystic fibrosis persist between countries.

PMID:
10858398
DOI:
10.1378/chest.117.6.1656
[Indexed for MEDLINE]

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