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Bioorg Med Chem Lett. 2000 May 1;10(9):911-4.

Non-electrostatic complexes with DNA: towards novel synthetic gene delivery systems.

Author information

1
UMR-7001 ENSCP/CNRS/Aventis Pharma Gencell, Vitry sur Seine, France.

Abstract

We have developed new DNA complexing amphiphile based on Hoechst 33258 interaction with DNA grooves. The synthesis and physicochemical characterisation of lipid/DNA complexes, as compared to that of classical lipopolyamine for gene delivery, are described and discussed.

PMID:
10853658
[Indexed for MEDLINE]

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