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Mayo Clin Proc. 2000 Jun;75(6):647-9.

Fournier gangrene associated with Crohn disease.

Author information

1
Hospitalist Group, Greater Baltimore Medical Center, Baltimore, MD 21204, USA.

Abstract

A 17-year-old boy presented with Fournier gangrene associated with previously undiagnosed Crohn ileocolitis. Fournier gangrene was managed by d├ębridement, broad-spectrum antibiotics, and hyperbaric oxygen. A diverting ileostomy was performed before skin grafting and scrotal reconstruction. Microscopy of a full-layer surgical sample from the terminal ileum revealed granulomas with multinucleated histiocytes, consistent with Crohn disease. Crohn disease was treated with mesalamine, metronidazole, 6-mercaptopurine, and infliximab. The patient was discharged on hospital day 32. At 6-month follow-up, reconstruction of his scrotum had completely healed. Ostomy output was normal.

PMID:
10852429
DOI:
10.4065/75.6.647
[Indexed for MEDLINE]

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