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Immunol Res. 2000;21(2-3):63-9.

A role for epithelial gammadelta T cells in tissue repair.

Author information

  • 1Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA. havran@scripps.edu

Abstract

My colleagues and I have a long-term interest in interactions between intraepithelial gammadelta T cells and neighboring epithelial cells. We have focused our studies on interactions in the thymus, skin, and intestine, and are investigating the development, specificity, and function of these gammadelta T cells. Our results have defined unique properties of these cells and support a specialized role for epithelial gammadelta T cells in immune surveillance, wound repair, inflammation, and protection from malignancy.

PMID:
10852103
DOI:
10.1385/IR:21:2-3:63
[PubMed - indexed for MEDLINE]
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