Format

Send to

Choose Destination
Neurology. 2000 Jun 13;54(11):2147-50.

Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor.

Author information

1
Department of Neurology, City of Hope National Medical Center, Duarte, CA 91010, USA. hopenshaw@coh.org

Abstract

Four of 10 patients who were enrolled on protocols of high-dose immunosuppression with peripheral blood stem cell rescue for MS experienced neurologic worsening while receiving recombinant human granulocyte colony-stimulating factor. There was improvement when methylprednisolone was given to three of the patients, but one patient died of respiratory failure. The mechanism of the neurologic worsening is uncertain.

PMID:
10851379
DOI:
10.1212/wnl.54.11.2147
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center