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Curr Opin Struct Biol. 2000 Jun;10(3):371-9.

Protein structure prediction in the postgenomic era.

Author information

1
Department of Biological Sciences, Brunel University, Uxbridge, UB8 3PH, UK. David.Jones@brunel.ac.uk.

Abstract

As the number of completely sequenced genomes rapidly increases, the postgenomic problem of gene function identification becomes ever more pressing. Predicting the structures of proteins encoded by genes of interest is one possible means to glean subtle clues as to the functions of these proteins. There are limitations to this approach to gene identification and a survey of the expected reliability of different protein structure prediction techniques has been undertaken.

PMID:
10851185
DOI:
10.1016/s0959-440x(00)00099-3
[Indexed for MEDLINE]

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