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Curr Opin Neurobiol. 2000 Jun;10(3):321-7.

Molecular determinants of presynaptic active zones.

Author information

1
Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294-0021, USA. garner@nrc.uab.edu

Abstract

The presynaptic cytoskeletal matrix (cytomatrix) assembled at active zones has been implicated in defining neurotransmitter release sites. Munc13, Rim, Bassoon and Piccolo/Aczonin are recently identified presynaptic cytomatrix proteins. These multidomain proteins are thought to organize the exocytotic and endocytotic machinery precisely at active zones.

PMID:
10851173
DOI:
10.1016/s0959-4388(00)00093-3
[Indexed for MEDLINE]

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