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Curr Opin Microbiol. 2000 Jun;3(3):298-302.

Protein arrays for gene expression and molecular interaction screening.

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Biorchard AS, Oslo, N-0281, Norway.


The array format has revolutionised biomedical experimentation and diagnostics, enabling ordered high-throughput analysis. During the past decade, classic solid phase substrates, such as microtitre plates, membrane filters and microscopic slides, were turned into high-density, chip-like structures. The concept of the arrayed library was central to this development which now extends from DNA to protein. The new and versatile protein array technology allows high-throughput screening for gene expression and molecular interactions. As a major platform for functional genomics, it is already on its way into medical diagnostics.

[Indexed for MEDLINE]

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