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Bioorg Med Chem Lett. 2000 May 15;10(10):1029-32.

Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38.

Author information

1
Eisai Research Institute, Andover, MA 01810, USA.

Abstract

Structurally simplified analogues of halichondrin B were prepared by total synthesis and found to retain potent cell growth inhibitory activity in vitro.

PMID:
10843209
DOI:
10.1016/s0960-894x(00)00150-5
[Indexed for MEDLINE]

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