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Mech Dev. 2000 Jun;94(1-2):257-60.

SOX8 expression during chick embryogenesis.

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Department of Pediatrics, Centre for Hormone Research, University of Melbourne, Royal Children's Hospital, Australia.


We have isolated the SOX8 gene from the chicken embryo. This gene shows a high degree of sequence homology to SOX9 and SOX10. Detailed analysis of SOX8 expression by whole-mount in situ shows a dynamic and restricted expression pattern during chick development. SOX8 is expressed in the somitic derivative, the dermomyotome, the developing heart, pancreas, enteric neurone system, limb and the neural tube. This is the first detailed expression analysis of SOX8 in any species

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