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Trends Microbiol. 2000 Jun;8(6):274-8.

The bactericidal action of penicillin: new clues to an unsolved mystery.

Author information

1
Dept of Microbiology, Molecular Biology and Biochemistry, University of Idaho, Moscow, Idaho 83844-3052, USA.

Abstract

The Staphylococcus aureus lrgAB operon was recently shown to inhibit extracellular murein hydrolase activity and increase tolerance to penicillin. Further characterization of this operon could provide novel insight into the dynamics of S. aureus cell wall metabolism and the mechanism of penicillin-induced lethality.

PMID:
10838585
DOI:
10.1016/s0966-842x(00)01762-5
[Indexed for MEDLINE]

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