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Curr Biol. 2000 May 18;10(10):R381-3.

Immunology of reproduction: protecting the placenta.

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1
Complement Biology Group, Department of Medical Biochemistry, UWCM, Cardiff, CF14 4XN, UK. morganbp@cf.ac.uk.

Abstract

The propensity of complement to damage self is controlled by expression of regulatory proteins. Recent results demonstrate that deleting just one of these regulators in mice causes complement to attack and destroy the embryo. These findings may have relevance to human pregnancy.

PMID:
10837212
[Indexed for MEDLINE]
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