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Curr Opin Genet Dev. 2000 Jun;10(3):306-9.

Inherited disorders of ion transport in the intestine.

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1
Finnish Genome Center, PO Box 21 (Tukholmankatu 2), 00014 University of Helsinki, Finland. juha.kere@helsinki.fi

Abstract

Within the past year, it has been established that the gene mutated in the human disorder congenital chloride diarrhea encodes a major Cl-/HCO3- exchanger at the apical membrane of gut epithelial cells. A major apical Na+/H+ exchanger has also been identified. New insight into metal ion absorption has been gained, and several new transporters without cognate diseases have been cloned.

PMID:
10826996
[Indexed for MEDLINE]
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