Send to

Choose Destination
Acta Biochim Pol. 1999;46(4):971-6.

Protection of cattle against bovine leukemia virus (BLV) infection could be attained by DNA vaccination.

Author information

Technical University of Gdańsk, Department of Microbiology, Poland.


The bovine leukemia virus (BLV) envelope gene encoding extracellular glycoprotein gp51 and transmembrane glycoprotein gp30 was cloned into a vehicle expression vector under the human cytomegalovirus (CMV) intermediate early promoter. The intramuscular injection of this plasmid vector generated a cellular immune response. Seven out of ten cows vaccinated with the DNA construct resisted a drastic challenge (500 BLV-infected lymphocytes as an infectious dose).

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Acta Biochemica Polonica, Inc.
Loading ...
Support Center