Synthesis of 1,2,3,7,8,9-hexahydrodipyrrins and secocorrins: important precursors for the construction of corrins

P A Jacobi; H Liu

doi:10.1021/ol990684j

Synthesis of 1,2,3,7,8,9-hexahydrodipyrrins and secocorrins: important precursors for the construction of corrins

Org Lett. 1999 Jul 29;1(2):341-4. doi: 10.1021/ol990684j.

Authors

P A Jacobi¹, H Liu

Affiliation

¹ Department of Chemistry, Wesleyan University, Middletown, Connecticut 06459-0180, USA. peter.a.jacobi@dartmouth.edu

PMID: 10822573
DOI: 10.1021/ol990684j

Abstract

[formula: see text] Hexahydrodipyrrins 15 (X=H2) have been prepared by two routes: Pd(0)-initiated coupling/cyclization of triflates 11 and alkyne amines 12 and reduction of semicorrins 26 (X=O).

Publication types

Research Support, U.S. Gov't, P.H.S.

MeSH terms

Chromatography, Thin Layer
Corrinoids
Cyclization
Oxidation-Reduction
Porphyrins / chemical synthesis*
Pyrroles / chemical synthesis*

Substances

Corrinoids
Porphyrins
Pyrroles

Grants and funding

GM38913/GM/NIGMS NIH HHS/United States