Highly oxygenated ecdysteroids from Vitex canescens root bark

Phytochemistry. 2000 Apr;53(8):921-4. doi: 10.1016/s0031-9422(99)00458-6.

Abstract

Highly oxygenated ecdysteroids, (24R)-11 alpha, 20,24-trihydroxyecdysone and 11 alpha,20,26-trihydroxyecdysone, have been isolated from the polar fraction of Vitex canescens root bark. The latter exists as two C-25 epimers which could be separated by reversed-phase HPLC.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromatography, High Pressure Liquid
  • Chromatography, Thin Layer
  • Ecdysteroids
  • Magnetic Resonance Spectroscopy
  • Plant Roots / chemistry
  • Plants, Medicinal*
  • Spectrometry, Mass, Fast Atom Bombardment
  • Stereoisomerism
  • Steroids / chemistry
  • Steroids / isolation & purification*
  • Vitex / chemistry*

Substances

  • 11,20,24-trihydroxyecdysone
  • 11,20,26-trihydroxyecdysone
  • Ecdysteroids
  • Steroids