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Adv Cancer Res. 2000;79:39-90.

The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation.

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1
Department of Pathology, Academic Medical Center, University of Amsterdam, The Netherlands.

Abstract

This article summarizes the structure, signal transduction and physiologic functions of the HGF/Met pathway, as well as its role in tumor growth, invasion, and metastasis. Moreover, it highlights recent studies indicating a role for the HGF/Met pathway in antigen-specific B-cell development and B-cell neoplasia.

PMID:
10818677
DOI:
10.1016/s0065-230x(00)79002-6
[Indexed for MEDLINE]

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