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Nat Neurosci. 2000 Jun;3(6):545-50.

Synaptic plasticity and dynamic modulation of the postsynaptic membrane.

Author information

1
Department of Pharmacology (APSIC), CMU, 1, Rue Michel-Servet, Université de Genève, 1211 Geneva 4, Switzerland. christian.luscher@medecine.unige.ch

Abstract

The biochemical composition of the postsynaptic membrane and the structure of dendritic spines may be rapidly modulated by synaptic activity. Here we review these findings, discuss their implications for long-term potentiation (LTP) and long-term depression (LTD) and propose a model of sequentially occurring expression mechanisms.

PMID:
10816309
DOI:
10.1038/75714
[Indexed for MEDLINE]
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