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Yeast. 2000 May;16(7):651-6.

The CUP1 promoter of Saccharomyces cerevisiae is inducible by copper in Pichia pastoris.

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Department of Biology, University of California San Diego, La Jolla, CA 92093-0322, USA.


We report the construction of a Pichia pastoris integrating vector which contains the inducible CUP1 promoter from Saccharomyces cerevisiae. We show that the promoter is indeed inducible by copper when used in P. pastoris and that the level of induction is dependent on the amount of copper in the medium.

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