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Exp Anim. 2000 Jan;49(1):51-5.

Characterization of a novel polycystic kidney rat model with accompanying polycystic liver.

Author information

1
Charles River Japan Inc., Kanagawa, Japan.

Abstract

A polycystic kidney rat model is being established from a Crj:CD (SD) rat strain. Unlike existing animal models of polycystic kidney disease, this mutant rat has a completely polycystic liver. Mating experiments revealed that the phenotype is controlled by an autosomal recessive gene. We propose that this gene be tentatively called the "rpc" gene.

PMID:
10803363
DOI:
10.1538/expanim.49.51
[Indexed for MEDLINE]
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