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Nat Med. 2000 May;6(5):513-9.

Mitochondrial control of cell death.

Author information

1
Centre National de la Recherche Scientifique, CNRS-ULR1599, Institut Gustave Roussy 24 rue Calmette Desmoulins, F-94805 Villejuif. kroemer@infobiogen.fr

Abstract

In many instances, permeabilization of mitochondrial membranes is a rate-limiting step of apoptotic or necrotic cell demise. This has important consequences for the pathophysiology of cell death, as well as for its pharmacological control.

PMID:
10802706
DOI:
10.1038/74994
[Indexed for MEDLINE]

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