Format

Send to

Choose Destination
Mol Plant Microbe Interact. 2000 May;13(5):572-7.

Multiresistance genes of Rhizobium etli CFN42.

Author information

1
Centro de Investigación sobre Fijación de Nitrógeno, and Facultad de Ciencias, Universidad Nacional Autónoma de México, Cuernavaca, Morelos.

Erratum in

  • Mol Plant Microbe Interact 2000 Jul;13(7):796.

Abstract

Multidrug efflux pumps of bacteria are involved in the resistance to various antibiotics and toxic compounds. In Rhizobium etli, a mutualistic symbiont of Phaseolus vulgaris (bean), genes resembling multidrug efflux pump genes were identified and designated rmrA and rmrB. rmrA was obtained after the screening of transposon-generated fusions that are inducible by bean-root released flavonoids. The predicted gene products of rmrAB shared significant homology to membrane fusion and major facilitator proteins, respectively. Mutants of rmrA formed on average 40% less nodules in bean, while mutants of rmrA and rmrB had enhanced sensitivity to phytoalexins, flavonoids, and salicylic acid, compared with the wild-type strain. Multidrug resistance genes emrAB from Escherichia coli complemented an rmrA mutant from R. etli for resistance to high concentrations of naringenin.

PMID:
10796024
DOI:
10.1094/MPMI.2000.13.5.572
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center