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J Foot Ankle Surg. 2000 Mar-Apr;39(2):124-30.

Antibiotic beads in the treatment of diabetic pedal osteomyelitis.

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1
Department of Surgery, Carl T. Hayden Vetrans' Affairs Medical Center, Phoenix, AZ 85012, USA.

Abstract

Antibiotic-impregnated polymethylmethacrylate (PMMA) beads have improved the outcome of osteomyelitis treatment in both experimental models and clinical trials. The primary benefit of antibiotic-impregnated PMMA beads is that they provide high local concentrations of antibiotic while systemic levels of antibiotic remain low. Little has been written about the specific use of antibiotic-impregnated PMMA beads in the treatment of diabetic pedal osteomyelitis. The authors review antibiotic-impregnated PMMA beads and provide examples of their use in the treatment of diabetic pedal osteomyelitis.

PMID:
10789104
[Indexed for MEDLINE]
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