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Bioorg Med Chem Lett. 2000 Apr 17;10(8):779-81.

Synthesis of a cyanopeptide-analogue with trypsin activating properties.

Author information

1
Institute of Pharmacy, Ernst-Moritz-Arndt-University, Pharmaceutical/Medicinal Chemistry, Greifswald, Germany. radau@pharmazie.uni-greifswald.de

Abstract

An efficient synthesis of a peptidic analogue of cyanobacterial metabolites with proposed serine protease inhibitory activity has been developed. Surprisingly, one trypsin activating compound was obtained.

PMID:
10782685
DOI:
10.1016/s0960-894x(00)00101-3
[Indexed for MEDLINE]

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