Send to

Choose Destination
Am J Cardiol. 2000 May 1;85(9):1151-3, A10.

Generic antiarrhythmics are not therapeutically equivalent for the treatment of tachyarrhythmias.

Author information

The Electrophysiology Service, Division of Cardiology, Department of Medicine, Columbia University and The New York Presbyterian Hospital, New York, NY, USA.


The consequences of antiarrhythmic drug formulation substitution were assessed by survey of 130 experts on arrhythmias. Fifty-four arrhythmia recurrences, 7 proarrhythmic events, and 3 deaths resulting from generic substitution are reported, thus raising serious concerns about both antiarrhythmic drug substitution and the adequacy of the generic drug approval process.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center