Format

Send to

Choose Destination
Curr Opin Immunol. 2000 Jun;12(3):295-300.

Regulation of T cell function by NK cell receptors for classical MHC class I molecules.

Author information

1
Centre d'Immunologie de Marseille-Luminy (CIML), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Campus Universitaire de Luminy, Marseille, 13288, France.

Abstract

Inhibitory receptors for MHC class I molecules were initially characterised on NK cells. Human and mouse NK cell receptors (NKRs) are also expressed on T cells, predominantly on a subset of memory-phenotype CD8(+) T cells. This review focuses on the precise determination of interactions between NKRs and MHC class I, as well as on the unexpected in vivo function of NKRs on T cells.

PMID:
10781402
DOI:
10.1016/s0952-7915(00)00090-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center