Format

Send to

Choose Destination
Curr Opin Immunol. 2000 Jun;12(3):282-8.

Tec family kinases in lymphocyte signaling and function.

Author information

1
Department of Pathology, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA. USA, USA. tschaeffer@uchichago.edu.

Abstract

The Tec kinases are required for full Ca(2+) mobilization in lymphocytes. Recent data suggest that this process occurs via a multiprotein complex that includes LAT and SLP-76 in T cells and BLNK/SLP-65 in B cells. Mutational analyses have revealed critical roles for Tec kinases in lymphocyte development and function.

PMID:
10781397
DOI:
10.1016/s0952-7915(00)00088-1
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center