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Lancet. 2000 Apr 15;355(9212):1351-7.

White blood cells 1: non-malignant disorders.

Author information

1
Department of Medicine, University of Illinois at Chicago School of Medicine, USA.

Abstract

Disorders of white cells are very common in clinical practice. White-cell development and numbers are controlled by a mixture of external stimuli including cytokines, matrix proteins, and accessory cells. Several different white-cell lineages are recognised; each has a role in host defence. Both white-cell deficiency and overproduction can lead to disease. Some forms of inherited white-cell deficiency are potentially treatable with gene therapy.

PMID:
10776761
DOI:
10.1016/S0140-6736(00)02125-5
[Indexed for MEDLINE]

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