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J Am Acad Dermatol. 2000 May;42(5 Pt 2):892-4.

Cowpox virus infection in an 11-year-old girl.

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Department of Dermatology and Allergology, Klinikum Innenstadt, Ludwig-Maximilians-University Munich, Munich, Germany.


We describe an 11-year-old girl with a cowpox virus infection, who presented with a 14-day-old crusted, ulcerated nodule on the chin/neck and a 6-day-old eroded blister on the left leg. The girl lived in a rural environment, had close contact to several cats from the neighborhood, and had an atopic predisposition. The presence of orthopox virus in the lesion on the left leg was demonstrated by electron microscopy (negative staining, transmission electron microscopy) and virus isolation. Classification as a cowpox virus was determined by polymerase chain reaction (PCR), followed by restriction enzyme digestion of the PCR product.

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