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Diagn Microbiol Infect Dis. 2000 Apr;36(4):275-8.

PCR fingerprinting analysis for differentiation of Streptococcus pneumoniae reinfection versus relapse.

Author information

1
R. M. Alden Research Laboratory, Santa Monica/UCLA Medical Center, Santa Monica, CA 90404, USA. shuntger@dent.ucla.edu

Abstract

Polymerase chain reaction fingerprint profiles of isolates obtained during an episode of pneumococcal pneumonia with bacteremia differed significantly from profiles of isolates obtained from the same patient during a subsequent episode of pneumococcal meningitis with bacteremia. Polymerase chain reaction fingerprinting provides a means of differentiating new infection from relapse, and may be a simple molecular tool for comparison of Streptococcus pneumoniae isolates.

PMID:
10764972
DOI:
10.1016/s0732-8893(00)00114-0
[Indexed for MEDLINE]

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