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Ned Tijdschr Geneeskd. 2000 Mar 25;144(13):617-22.

[Pulmonary hemorrhage with respiratory insufficiency in Henoch- Schoenlein purpura].

[Article in Dutch]

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Afd. Interne Geneeskunde-Intensive Care Beademing, Academisch Ziekenhuis, Groningen.


A 20-year-old woman presented with abdominal pain, purpura on the extremities, and arthralgia. The diagnosis of Henoch-Schönlein purpura was made based on granular IgA deposits in the vessels in a skin biopsy. Three weeks after onset of these symptoms, she developed glomerulonephritis and diffuse alveolar haemorrhage; she developed respiratory failure and needed mechanical ventilation. She recovered upon treatment with corticosteroids. Diffuse alveolar bleeding has occasionally been reported in adults with Henoch-Schönlein purpura; this is the first report from the Netherlands.

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