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Trends Microbiol. 2000 Apr;8(4):189-91.

The suckling mouse model of cholera.

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Dept. of Microbiology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78284-7758, USA.


Vibrio cholerae colonization of the suckling mouse intestine is a commonly used animal model for the human diarrheal disease cholera. This model has a number of advantages as well as disadvantages, and has been extremely useful in the identification and characterization of proven and putative virulence factors involved in human cholera.

[Indexed for MEDLINE]

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