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Curr Opin Neurobiol. 2000 Apr;10(2):180-6.

Memory trace reactivation in hippocampal and neocortical neuronal ensembles.

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Arizona Research Laboratories, Division of Neural Systems, Memory and Aging, PO Box 24-5115, Tucson, AZ 85724-5115, USA.


During active behavior, patterns of hippocampal and neocortical neuronal activity reflect ongoing inputs and their contexts. Recent neurophysiological investigations have shown that during 'off-line' periods, traces of these experiences are spontaneously reactivated in both structures. Although the functional importance of this phenomenon remains to be demonstrated, it does provide clues about the nature and mechanisms of memory retrieval and consolidation.

[Indexed for MEDLINE]

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