[Mesenteric vein and inferior vena cava thrombosis: disseminated intravascular coagulation and/or G 20210 A mutation of the prothrombin gene?]

Ann Fr Anesth Reanim. 2000 Jan;19(1):42-6. doi: 10.1016/s0750-7658(00)00124-6.
[Article in French]

Abstract

The authors report the case of a 30-year-old man who died from pulmonary embolism and multiorgan failure caused by mesenteric and inferior vena cava thrombosis. The patient was found heterozygous for the prothrombin gene variant (G 20210 A). The family study showed the same asymptomatic anomaly in his brother. This recently described mutation is associated with an increased risk for venous thrombosis. The investigations and treatment of mesenteric venous thrombosis are discussed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Disseminated Intravascular Coagulation / complications*
  • Disseminated Intravascular Coagulation / genetics
  • Fatal Outcome
  • Genetic Predisposition to Disease
  • Heterozygote
  • Humans
  • Male
  • Mesenteric Vascular Occlusion / etiology*
  • Mesenteric Vascular Occlusion / genetics
  • Mesenteric Veins*
  • Multiple Organ Failure / etiology
  • Mutation / genetics*
  • Prothrombin / genetics*
  • Pulmonary Embolism / etiology
  • Vena Cava, Inferior*
  • Venous Thrombosis / etiology*
  • Venous Thrombosis / genetics

Substances

  • Prothrombin