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Brain Res Brain Res Rev. 2000 Apr;32(1):121-9.

Modulation of coupling between retinal horizontal cells by retinoic acid and endogenous dopamine.

Author information

1
Neurobiology, University of Oldenburg, Germany. reto.weiler@uni-oldenberg.de

Abstract

The regulation of electrical coupling between retinal neurons appears to be an important component of the neuronal mechanism of light adaptation, which enables the retina to operate efficiently over a broad range of light intensities. The information about the ambient light conditions has to be transmitted to the neuronal network of the retina and previous evidence has indicated that dopamine is an important neurochemical signal. In addition, recent studies suggest that another important chemical signal is retinoic acid, which is a light-correlated byproduct of the phototransduction cycle. This review summarizes the latest findings about the effects of dopamine and retinoic acid on gap junctional coupling in the retinas of mouse, rabbit and fish.

PMID:
10751661
[Indexed for MEDLINE]

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