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Curr Opin Microbiol. 2000 Apr;3(2):126-31.

The fungal GATA factors.

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CNRS UMR 8621, Institut de Génétique et Microbiologie, Université Paris-Sud, Centre d'Orsay, 91405, France. scazzocchio@igmors.u-psud. fr


The DNA-binding domains of eucaryotic GATA factors comprise a four-cysteine Zn finger and an adjacent basic region. Fungal GATA factors regulate nitrogen metabolism, light induction, siderophore biosynthesis and mating-type switching. Hydrophobic interactions determine binding-site specificity. Interactions with other factors may determine promoter specificity. One GATA factor has recently been shown to determine a drastic chromatin rearrangement.

[Indexed for MEDLINE]

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