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Curr Opin Microbiol. 2000 Apr;3(2):144-8.

Diversity of homology-dependent gene silencing strategies in fungi.

Author information

1
Institut Jacques Monod, UMR 7592: CNRS/Université Paris, Paris, 75251, France. faugeron@ijm.jussieu.fr

Abstract

The experimental introduction of DNA in fungi has revealed a variety of gene inactivation strategies triggered in response to the presence of homologous nucleic acid sequences. These homology effects reveal distinct classes of gene inactivation resulting from hypermutation or relying on regulatory mechanisms that operate at either the transcriptional or the post-transcriptional level.

PMID:
10744998
DOI:
10.1016/s1369-5274(00)00066-7
[Indexed for MEDLINE]

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