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Microbes Infect. 2000 Feb;2(2):223-9.

Primate models of AIDS.

Author information

1
JODI Research Inc., Wexford, Pennsylvania and the Marion Merrell Dow Laboratory of Viral Pathogenesis, University of Kansas School of Medicine, Kansas, City, Kansas, USA.

Abstract

The primate models of AIDS provide insights into pathogenesis, transmission, and immune responses to infection and are useful in testing vaccines and drugs. The HIV-1/chimpanzee, SIV(mac)/macaque, and SHIV/macaque models are the most widely used. The advantages and drawbacks of these and other models are discussed.

PMID:
10742694
DOI:
10.1016/s1286-4579(00)00266-5
[Indexed for MEDLINE]

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