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Microbes Infect. 2000 Feb;2(2):213-21.

Turning a corner on HIV neutralization?

Author information

1
Montana Biotechnology Center, The University of Montana, Missoula, MT 59812, USA.

Abstract

HIV vaccine development has been hampered by the inability of conventional immunogens to elicit antibodies capable of neutralizing primary isolates of the virus. Recent studies using 'fusion-competent' immunogens that capture transitional intermediate structures of the functioning envelope protein suggest that this goal may now be achievable.

PMID:
10742693
DOI:
10.1016/s1286-4579(00)00267-7
[Indexed for MEDLINE]

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