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Microbes Infect. 2000 Feb;2(2):157-66.

Temperature-regulated expression of bacterial virulence genes.

Author information

1
School of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA.

Abstract

Virulence gene expression in most bacteria is a highly regulated phenomenon, affected by a variety of parameters including osmolarity, pH, ion concentration, iron levels, growth phase, and population density. Virulence genes are also regulated by temperature, which acts as an 'on-off' switch in a manner distinct from the more general heat-shock response. Here, we review temperature-responsive expression of virulence genes in four diverse pathogens.

PMID:
10742688
DOI:
10.1016/s1286-4579(00)00272-0
[Indexed for MEDLINE]

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