Format

Send to

Choose Destination
Bioorg Med Chem Lett. 2000 Mar 20;10(6):597-600.

Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine.

Author information

1
Glaxo Wellcome Research and Development, Stevenage, Hertfordshire, UK. rjy40958@glaxowellcome.co.uk

Abstract

The synthesis and in vitro evaluation of the acetamidine derivatives of hetero-substituted lysine and homolysine analogues have identified potent inhibitors of human nitric oxide synthase enzymes, including examples with marked selectivity for the inducible isoform.

PMID:
10741561
DOI:
10.1016/s0960-894x(00)00055-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center