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Mol Cell Probes. 2000 Feb;14(1):55-6.

A common polymorphism in the human insulin-like growth factor binding protein 3 gene.

Author information

1
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA.

Abstract

A common polymorphism generated by an A to C transition at nucleotide 7580 in the third intron of the insulin-like growth factor binding protein 3 gene was found. This polymorphism can be identified by Nde 1 restriction of genomic DNA amplified with a specifically designed restriction enzyme site-generating oligonucleotide primer. The frequency of the A and C alleles was estimated at 0.6 and 0.4 in the Caucasians, 0.63 and 0.37 in Blacks, respectively.

PMID:
10722794
DOI:
10.1006/mcpr.1999.0282
[Indexed for MEDLINE]

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