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Scand J Rheumatol. 2000;29(1):44-51.

Co-existence of chronic fatigue syndrome with fibromyalgia syndrome in the general population. A controlled study.

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1
Department of Medicine, University of Western Ontario, London, Canada. kevin.white@lhsc.on.ca

Abstract

OBJECTIVE:

To determine the proportion of adults with fibromyalgia syndrome (FMS) in the general population who also meet the 1988 Centre for Disease Control (CDC) criteria for chronic fatigue syndrome (CFS).

METHODS:

Seventy-four FMS cases were compared with 32 non-FMS controls with widespread pain and 23 with localized pain, all recruited in a general population survey.

RESULTS:

Among females, 58.0% of fibromyalgia cases met the full criteria for CFS, compared to 26.1% and 12.5% of controls with widespread and localized pain, respectively (p=0.0006). Male percentages were 80.0, 22.2, and zero, respectively (p=0.003). Compared to those with FMS alone, those meeting the case definitions for both FMS and CFS reported a worse course, worse overall health, more dissatisfaction with health, more non-CFS symptoms, and greater disease impact. The number of total symptoms and non-CFS symptoms were the best predictors of co-morbid CFS.

CONCLUSIONS:

There is significant clinical overlap between CFS and FMS.

PMID:
10722257
[Indexed for MEDLINE]
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