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J Psychiatry Neurosci. 2000 Jan;25(1):53-7.

Early- versus late-onset bipolar II disorder.

Author information

1
Department of Psychiatry, Morgagni Public Hospital, Forlì, Italy. f.benazzi@fo.nettuno.it

Abstract

OBJECTIVE:

To compare the clinical features and the outcome between patients with early- and late-onset bipolar II disorder.

DESIGN:

Case series.

SETTING:

Outpatient private practice.

PATIENTS:

One hundred and seventy-nine consecutive outpatients with bipolar II disorder presenting for treatment of a major depressive episode.

OUTCOME MEASURES:

Duration of illness, severity of depression, recurrences, psychosis, chronicity, atypical features and comorbidity.

RESULTS:

Patients with early-onset (before 20, 25 or 30 years of age) bipolar II disorder had a significantly longer duration of illness and more recurrences compared with patients with late-onset (after 20, 25 or 30 years of age) bipolar II disorder. All other variables were not significantly different between the 2 groups.

CONCLUSIONS:

Indicators of worse outcome (severity of depression, psychosis, chronicity, comorbidity) were not significantly different between patients with early- and late-onset bipolar II disorder.

PMID:
10721685
PMCID:
PMC1407699
[Indexed for MEDLINE]
Free PMC Article
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