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J Cataract Refract Surg. 2000 Mar;26(3):382-5.

Effect of tropicamide on aqueous flare before and after cataract surgery.

Author information

1
Department of Ophthalmology, University of Vienna, Vienna, Austria.

Abstract

PURPOSE:

To examine the effect of tropicamide on flare intensity under phakic and pseudophakic conditions and to differentiate between the possible mechanisms of action of tropicamide on aqueous flare.

SETTING:

Department of Ophthalmology, Vienna General Hospital, University of Vienna, Vienna, Austria.

METHODS:

In this prospective study, aqueous flare was measured with the laser flare-cell meter in 20 eyes of 20 patients with age-related cataract enrolled for cataract surgery. Measurements were performed before and 30, 90, and 180 minutes after pupil dilation with tropicamide 0.5%. This measurement was performed in the phakic eye on the day before surgery and in the pseudophakic eye on postoperative days 1, 3, 7, and 28.

RESULTS:

After tropicamide instillation, aqueous flare decreased preoperatively and on all postoperative days. There was a continuous flare decrease until 3 hours after instillation, reaching a maximum decrease of about 30%. Pupil diameter reached its maximum after 30 minutes.

CONCLUSION:

Tropicamide significantly decreased aqueous flare, seemingly by pharmacological means, not volumetric changes. The time between drug application and measurement should be kept constant.

PMID:
10713233
[Indexed for MEDLINE]

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