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Chem Biol. 2000 Mar;7(3):R57-61.

Tyrosine sulfation: a modulator of extracellular protein-protein interactions.

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1
Departments of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.

Abstract

Tyrosine sulfation is a post-translational modification of many secreted and membrane-bound proteins. Its biological roles have been unclear. Recent work has implicated tyrosine sulfate as a determinant of protein-protein interactions involved in leukocyte adhesion, hemostasis and chemokine signaling.

PMID:
10712936
DOI:
10.1016/s1074-5521(00)00093-4
[Indexed for MEDLINE]
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