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Biochim Biophys Acta. 2000 Mar 7;1477(1-2):122-45.

Structure-function relationships of glutamine synthetases.

Author information

1
UCLA-DOE Laboratory of Structural Biology and Molecular Medicine, Departments of Chemistry, Biochemistry and Biological Chemistry, University of California, Los Angeles, 201 MBI, Box 951570, Los Angeles, CA 90095-1570, USA. david@mbi.ucla.edu

Abstract

As a highly regulated enzyme at the core of nitrogen metabolism, glutamine synthetase has been studied intensively. We review structural and functional studies of both bacterial and eukaryotic glutamine synthetases, with emphasis on enzymatic inhibitors.

PMID:
10708854
DOI:
10.1016/s0167-4838(99)00270-8
[Indexed for MEDLINE]

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